Publications

Publications marked with an * were directly funded through the KFO 329

*Mangold, N., …, Schermer, B., Benzing, T., Brinkkoetter, P. T. & Hagmann, H. The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development. Cells 10, 2464 (2021).

*Koehler, F. C., Späth, M. R., Hoyer-Allo, K. J. R. & Müller, R.-U. Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney Injury. Nephron 1–5 (2021). doi:10.1159/000517733

*Butt, L., Unnersjö-Jess, D., Höhne, M., Schermer, B., Edwards, A. & Benzing, T. A mathematical estimation of the physical forces driving podocyte detachment. Kidney Int. S0085-2538(21)00728–6 (2021). doi:10.1016/j.kint.2021.06.040

*Rieckher, M., Garinis, G. A. & Schumacher, B. Molecular pathology of rare progeroid diseases. Trends Mol. Med. 27, 907–922 (2021).

*Schumacher, B., Pothof, J., Vijg, J. & Hoeijmakers, J. H. J. The central role of DNA damage in the ageing process. Nature 592, 695–703 (2021).

*Fabretti, F., ..., Weber, L. T., Thiele, H., Altmueller, J., Schermer, B., Beck, B. B. & Habbig, S. Expanding the Spectrum of FAT1 Nephropathies by Novel Mutations That Affect Hippo Signaling. Kidney Int. Rep. 6, 1368-1378 (2021).

*Benzing, T. & Salant, David J. Insights into Glomerular Filtration and Albuminuria. N. Engl. J. Med. 384, 1437-1446 (2021).

*Unnersjö-Jess, D., Butt, L., Höhne, M., ..., Brinkkötter, P. T., Wernerson, A., Schermer, B., Benzing, T., ... & Blom, H. A fast and simple clearing and swelling protocol for 3D in-situ imaging of the kidney across scales. Kidney Int. 99, 1010–1020 (2021).

*da Silva, P. F. L. & Schumacher, B. Principles of the Molecular and Cellular Mechanisms of Aging. J. Invest. Dermatol. 141, 951–960 (2021).

*Talyan, S., ..., Altmüller, J., Brinkkötter, P., Schermer, B., Benzing, T., Kann, M., Müller, R.-U. & Dieterich, C. CALINCA—A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. Cells 10, 692 (2021).

*Meyer, D. H. & Schumacher, B. BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy. Aging Cell 20, e13320 (2021).

*Wang, S., Meyer, D. H. & Schumacher, B. H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat. Struct. Mol. Biol. 36, 1165-1177 (2020).

*Braun, F., …, Schermer, B., Benzing, T., Huber, T. B., Beyer, A., Stippel, D., Kurschat, C. E. & Müller, R.-U. The proteomic landscape of small urinary extracellular vesicles during kidney transplantation. J. Extracell. Vesicles 10, e12026 (2020).

*Unnersjö-Jess, D. Towards all-optical kidney pathology? Wiley Analytical Science (2020).

*Lopes, A. F. C., Bozek, K., Herholz, M., Trifunovic, A., Rieckher, M. & Schumacher, B. A C. elegans model for neurodegeneration in Cockayne syndrome. Nucleic Acids Res. 48, 10973-10985 (2020).

*Chatzidoukaki, O., Goulielmaki, E., Schumacher, B. & Garinis, G. A. DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends Genet. 36, 777–791 (2020).

*Williams, A. B., …, Bloch, W. & Schumacher, B. Restoration of Proteostasis in the Endoplasmic Reticulum Reverses an Inflammation-Like Response to Cytoplasmic DNA in Caenorhabditis elegans. Genetics 212, 1259–1278 (2019).

*Benzing, T. Molecular Design of the Kidney Filtration Barrier. Trans. Am. Clin. Climatol. Assoc. 131, 125–139 (2020).

*Erger, F., …, Habbig, S., …, Beck, B. B. & Altmüller, J. cfNOMe — A single assay for comprehensive epigenetic analyses of cell-free DNA. Genome Med. 12, 54 (2020).

*Matin, M., Mörgelin, M., Stetefeld, J., Schermer, B., Brinkkoetter, P. T., Benzing, T., Koch, M. & Hagmann, H. Affinity-Enhanced Multimeric VEGF (Vascular Endothelial Growth Factor) and PlGF (Placental Growth Factor) Variants for Specific Adsorption of sFlt-1 to Restore Angiogenic Balance in Preeclampsia. Hypertension 76, 1176–1184 (2020).

*Butt, L., Unnersjö-Jess, D., Höhne, M., …, Hackl, M. J., Walz, G., Brinkkoetter, P. T., …, Beck, B. B., Brismar, H., Blom, H., Schermer, B. & Benzing, T. A molecular mechanism explaining albuminuria in kidney disease. Nat. Metab. 2, 461–474 (2020).

*Johnsen, M., …, Beyer, A., Benzing, T., Schermer, B., Burst, V. & Müller, R.-U. The Integrated RNA Landscape of Renal Preconditioning against Ischemia-Reperfusion Injury. J. Am. Soc. Nephrol. 31, 716-730 (2020).

*Koehler, S., …, Hoehne, M., …, Beck, B. B., Höhfeld, J., Schermer, B., Benzing, T., Brinkkoetter, P. T. & Rinschen, M. M. Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis. J. Am. Soc. Nephrol. 31, 544–559 (2020).

*Yigit, G., …, Beck, B. B., Nürnberg, P., Dieterich, C., Wollnik, B., Matsumoto, N. & Altmüller, J. The recurrent post-zygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuro-ectodermal phenotype. Hum. Mutat. 41, 591-599 (2020).